Identifying Placebo Effects with Data from Clinical Trials

S-Tier
Journal: Journal of Political Economy
Year: 2006
Volume: 114
Issue: 2
Pages: 236-256

Score contribution per author:

8.043 = (α=2.01 / 1 authors) × 4.0x S-tier

α: calibrated so average coauthorship-adjusted count equals average raw count

Abstract

A medical treatment is said to have placebo effects if patients who are optimistic about the treatment respond better to the treatment. This paper proposes a simple test for placebo effects. Instead of comparing the treatment and control arms of a single trial, one should compare the treatment arms of two trials with different probabilities of assignment to treatment. If there are placebo effects, patients in the higher-probability trial will experience better outcomes simply because they believe that there is a greater chance of receiving treatment. This paper finds evidence of placebo effects in trials of antiulcer and cholesterol-lowering drugs.

Technical Details

RePEc Handle
repec:ucp:jpolec:v:114:y:2006:i:2:p:236-256
Journal Field
General
Author Count
1
Added to Database
2026-01-26